Complete the train.

Complete the laboratory.

Complete the treatment plant.

Finish the game on Hard difficulty.

Finish the game without saving.

Finish the game without using a recovery item (including Green Chemicals).

Defeat Centurion.

Fight off the Proto Tyrant.

Defeat Queen Leech.

Defeat an enemy with a critical-hit headshot.

Defeat a zombie by stomping on them.

Change into a costume.

Defeat an enemy with a knife.

Shoot down a Hunter or an Eliminator while they are jump attacking in the air.

Create a Custom Handgun.

Defeat Mimicry Marcus with a Molotov Cocktail or a Napalm Grenade.

Obtain all keys and use them all.

Combine every type of herb with each other.

Defeat 16 bats in the church.

Play the piano using Rebecca.

Get picked up by the Infected Bat.

Finish Leech Hunter with rank A.

Collect all of only one color of Leech Charms.

Kill 50 enemies with the Death Stare at full charge.