Defended yourself against the Big Sister without dying.

Defeated the Preacher.

Installed the third upgrade to a weapon.

Researched a Splicer with the Research Camera.

Got through a Gather with no damage and no one getting to the Little Sister.

Joined forces with Sinclair in Ryan Amusements.

Adopted a new Little Sister for the very first time.

Defended yourself against Lamb's Assault in the train station.

Found your way back into the ruins of Rapture.

The player has defeated Atlas

The player has either Harvested or Rescued every possible Little Sister

The player has fully upgraded three weapons