Complete the subplot involving Keira Metz.

Beat the Last Chapter Without Dying on Normal Difficulty or Harder

Find the Strange Relic

Kill an Enemy While Playing as an Alternate Character Costume Other Than Drake

Finish the Game on Easy Without Changing the Difficulty

Finish the Game on Hard Without Changing the Difficulty

Kill 50 Enemies with the 92FS-9mm

Kill 20 Enemies with the Pistole

Kill 50 Enemies with the M4

Find 20 Treasures

Kill 20 Enemies with Gunfire While Hanging

Kill 20 Enemies by Shooting from the Hip (without aiming)

Kill 50 Enemies by Melee-Attacking from Behind