The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has either Harvested or Rescued every possible Little Sister

The player has broken Fontaine's mind control

The player has fully upgraded two weapons

Unlock a part

The player has completed Sander Cohen's great masterpiece

The player has successfully invented all possible ammo types

Hit the jackpot at a slot machine

The player has fully researched the Leadhead Splicer

Win an online singles match (3 sets of 3 games / Super Tie-Break) without losing a game.

The player has acquired at least one weapon upgrade

Found your way back into the ruins of Rapture.

Get a 2X Multiplier