Kill 30 enemies with the Plasma Cutter

Dismember 20 Limbs

Place a sticker

Choose a costume for your sackperson with at least one item on your head, at least one item on your body, and a material

The player has completed the game without harvesting any Little Sisters

The player has become a Big Daddy

The player has fully upgraded three weapons

The player has broken Fontaine's mind control

The player has defeated Andrew Ryan

The player has completed Sander Cohen's great masterpiece

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has successfully invented at least one item

The player has acquired at least one weapon upgrade