Release Melissa from her Trap.

First kill with a Scalpel.

First kill with a Bat.

Unlock 5 locked doors.

First kill with a Crutch.

First kill with a Mop Handle.

Used Health Syringe for the first time.

Died once.

Find your first Patient File.

Kill first minion.

Find your first Asylum File.

Unlock first container.

Complete the Isengard level in the single player "War of the Ring" Campaign.