Attack and destroy a monster.

Harvest some leather.

Use planks and sticks to make a sword.

Craft a workbench with four blocks of wooden planks.

Open your inventory.

Break into every locked door using shivs

Collect all comics

Find all workbenches

Upgrade and then break one of every melee weapon

Pet Buckley the dog

Open all safes

While in stealth, turn off the spotlight generator in Pittsburgh

Find a comic