Kill 100 Enemies with Headshots

Defeat 50 Enemies with Hand-to-Hand Combat

Score a goal using a low shot

Have 7 or more max red hearts at one time

Make 3 deals with the devil in one run

Collect 2 of either Roid Rage, The Virus, Growth Hormones, Experimental Treatment, or Speed Ball

Kill 20 Enemies with Headshots

Defeat 20 Enemies with Hand-to-Hand Combat

Find the hidden item boxes at the end of the Zone

Finish the Game on Easy Without Changing the Difficulty

Defeat 250 Enemies with Headshots

Kill 3 Enemies with 1 Explosion