Upgraded Vitality and Posture to their limit

Attained the "Purification" ending

Attained the "Immortal Severance" ending

Defeated the "Demon of Hatred"

Defeated the "Great Colored Carp".

Used the Mortal Blade to sever the Guardian Ape's undying

Grasped the inner mysteries of any combat style

Defeated the "Corrupted Monk"

Defeated "Great Shinobi - Owl"

Defeated the "Guardian Ape"

Unlock all trophies.

Look at the one-eyed statue in the infirmary with Wesker (must be in third-person view).