The player has completed Sander Cohen's great masterpiece

The player has fully researched the Spider Splicer

Defeat Stage 3 Nemesis.

Complete "Emotion of the Ocean".

Revive a partner.

Follow Nicholai deeper underground.

Unlock all safes, lockers, strongboxes, and pickable locks.

Leave the clock tower plaza.

Defeat zombie Brad.

Defeat Nemesis on the rooftop.

Place all jewels in the clock tower monument.

Defeat two enemies with a single shot.