The player has taken a picture of Sander Cohen's corpse

Fully upgrade four weapons

The player has fully upgraded three weapons

The player has fully researched the Spider Splicer

The player has fully researched the Thuggish Splicer

Take at least one photo in every research group

In CitC, got a kill with each weapon and vigor (except Bucking Bronco).

Used Ironsides to collect 20 rounds of ammo or more in Burial at Sea - Episode 2.

While invisible, used Peeping Tom to knock out 15 enemies with a melee attack.

Damaged fifteen foes with an exploding enemy, using the Radar Range in Burial at Sea - Episode 1.

Made 5 enemies explode with the Radar Range in Burial at Sea - Episode 1.

Froze 2 enemies with the same Old Man Winter trap in Burial at Sea - Episode 1.

Destroyed ten Turrets in Burial at Sea - Episode 1.