Bought one Plasmid or Tonic Slot at a Gatherer's Garden.

Defended yourself against the Big Sister without dying.

Killed an enemy with its own projectile.

Upgraded a weapon at a Power to the People Station.

Used the Hack Tool to hack an object at a distance.

The player has completed the game without harvesting any Little Sisters

The player has successfully invented all possible ammo types

Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks

The player has either Harvested or Rescued every possible Little Sister

The player has broken Fontaine's mind control

The player has fully upgraded three weapons

The player has completed Sander Cohen's great masterpiece