Flew through the O ring in the Sentinel Boss Battle

Killed 2000 enemies

Raised One Combat Reflex to Master Level

Light 20 enemies on fire

Defeated Weapon 11 (Deadpool)

Killed 200 enemies with Claw Spin

Got 6 enemies airborne at once

Killed 25 Ghosts with their own weapon

Destroyed all objects in the grocery store fight with Fred Dukes (The Blob)

Killed 6 enemies with a single attack

Raised one Mutagen to level 3

Dismembered 100 enemies

Found 1/2 of all Dog Tags in the game