Took the G.O.A.T.

The player has completed the game without harvesting any Little Sisters

The player has become a Big Daddy

The player has either Harvested or Rescued every possible Little Sister

Max out all possible research

Fully research the Little Sister

The player has fully upgraded three weapons

The player has completed Sander Cohen's great masterpiece

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has fully researched the Spider Splicer

Hit the jackpot at a slot machine

Fully research the Rosie