The player has entered Sander Cohen's personal quarters

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has fully upgraded two weapons

The player has fully researched the Spider Splicer

The player has completed Sander Cohen's great masterpiece

The player has fully upgraded one weapon

Complete Chapter 1 on any difficulty setting

Unlock new weapons by hitting a Convoy

Save a Buddy from captivity

The player has successfully completed 50 hacks

The player has acquired at least one weapon upgrade

The player has successfully hacked a security camera

The player has taken a Research Photo of the highest grade