The player has defeated Andrew Ryan

Fully research the Bouncer

The player has purchased every slot in one of the Plasmid or Tonic tracks

Fully research the Houdini Splicer

The player has fully researched the Spider Splicer

The player has fully upgraded one weapon

The player has successfully invented at least one item

The player has defeated Peach Wilkins

The player has successfully completed 50 hacks

The player has taken a Research Photo of the highest grade

The player has defeated the crazed Dr. Steinman

The player has successfully hacked a turret

The player has successfully hacked a vending machine