The player has become a Big Daddy

The player has either Harvested or Rescued every possible Little Sister

The player has broken Fontaine's mind control

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has fully upgraded two weapons

The player has completed Sander Cohen's great masterpiece

The player has successfully invented at least one item

The player has acquired at least one weapon upgrade

The player has taken at least one Research Photo of a Splicer

The player has purchased one slot in any Plasmid or Tonic track

The player has successfully hacked a safe

Find and bloom a secret flower.