Craft a potion recipe for the first time

Finish "Royal Garden" level.

Defeat Mutated Odur.

Finish "Sea of Trees" level.

Unlock a plague weapon for the first time.

Start recalling for the first time.

Rest at the beacon for the first time.

Knock 2 enemies to their deaths with one use of Roadhog's Whole Hog in Quick or Competitive Play.

Find one of George's audio cassette.

Capture 4 enemies in a single use of Zarya's Graviton Surge in Quick or Competitive Play.

Try to leave via the front door.

Complete the game.