Max out the Health Bar

Unlock all the entries for every enemy file in the status menu

Complete all Secret Missions

Finish the Game on Hard Mode

Discovered all named locations in The Highlands, Thousand Cuts, and Wildlife Exploitation Preserve

Purchase all of Dante's Skills

Collect all Guns

Collect 25,000 Red Orbs

Unlock 50% of all entries for every enemy file in the status menu

Perform an S Rank Combo using Alastor

Survive an encounter with Nelo Angelo

Complete a Secret Mission

100 Chainsaw Combos.