Complete all levels in The Wedding

The player has defeated Atlas

The player has become a Big Daddy

Acquire all upgrades for all weapons

Purchased every slot in all four Plasmid and Tonic tracks

Max out all possible research

Fully research the Nitro Splicer

The player has taken a picture of Sander Cohen's corpse

The player has defeated Andrew Ryan

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has completed Sander Cohen's great masterpiece

The player has successfully invented all possible ammo types