Bad guys make it clear who the boss is.

Bad guys never share their food.

The player has defeated Atlas

Take the Prince for a ride.

Fully research the Little Sister

The player has either Harvested or Rescued every possible Little Sister

The player has broken Fontaine's mind control

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has taken a picture of Sander Cohen's corpse

Take over all territory in the Warren.

The player has restored the forests of Arcadia

The player has successfully invented at least one item

The player has acquired at least one weapon upgrade