Use your Eagle Vision to scan a Glyph in the environment.

Synchronize 10 View Points.

Pickpocket 1000 Florins.

Perform a Leap of Faith from the Top of Florence's Giotto's Campanile.

Sprint for 100 meters.

Break out of Abstergo.

Unlock all safehouses.

Uncovered the secret of Dionysus Park.

Gathered 600 ADAM with Little Sisters.

Defeated the Preacher.

Spent 2000 dollars at Vending Machines.

Killed an enemy with its own projectile.

Bought one Plasmid or Tonic Slot at a Gatherer's Garden.