The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has broken Fontaine's mind control

The player has successfully invented all possible ammo types

The player has fully upgraded two weapons

The player has successfully hacked a security camera

The player has fully upgraded one weapon

The player has successfully invented at least one item

The player has defeated Peach Wilkins

The player has taken at least one Research Photo of a Splicer

The player has successfully hacked a safe

The player has performed at least one successful hack

The player has shocked an enemy in the water