Complete Chapter 1 in Jake's campaign.

Defeat 100 Afflicted in the main campaign.

Complete Chapter 5 in Leon's campaign.

Complete Chapter 4 in Leon's campaign.

Defeat two enemies with one shot in the main campaign.

Complete Chapter 2 in Leon's campaign.

Rescue two female survivors at the cathedral.

Complete the tutorial.

Have Moira stun an enemy and Claire follow up with a physical attack in the main campaign.

Collect 1,000 Omnitrix Energy Orbs

Destroy all targets and structures while making your way up the river.

Escape the Past.

Retrieve the dossier and the defector from Hue City.