Destroy all enemies on vehicles during the prison break.

Take down Castro with a headshot.

Complete your first assassination mission for Lorenzo Il Magnifico.

Complete DNA Sequence 4.

Discover the Assassin's Tomb inside the catacombs under Santa Maria Novella.

Create a goal with a player with the Playmaker Speciality

Kill a Rockstar or someone with this Trophy in a public multiplayer match.

Reunited with your original Little Sister.

Gained access to Lamb's stronghold.

Killed 50 enemies using only hacked Security.

Uncovered the secret of Dionysus Park.

Defeated the Preacher.