Use a cannon to defeat a zealot.

Rescue Ashley as she's being carried away by the enemy.

Complete a game at the shooting range.

Upgrade a weapon.

Parry an enemy with a knife.

Open your inventory.

Have Moira stun an enemy and Claire follow up with a physical attack in the main campaign.

Finish the game on Normal Mode with any character

Defeat Doppelganger

Defeat Lady

Defeat Geryon

Reach the highest level for any gun with Dante