Kill 3 enemies at once with a sub-weapon.

Complete Claire's story on "Standard" or "Hardcore" with an S rank.

Destroy all Mr. Raccoons.

Combine two items together.

Make it to the police station.

Escape from the sewers.

Clear the game without opening the item box.

Complete Leon's story on "Hardcore" game mode.

Complete Leon's story on "Standard" or "Hardcore" with an S rank.

Open all of the safes and locks in the game.

Solve the Goddess Statue puzzle.

Complete the first Hospital sequence

Defeat Algos' first form