Use psychostimulants.

Put an unrelated object on a shadow plinth.

Shoot and knock back Marguerite while she's leaping at you.

Use a lock pick to open something.

Close an open door by yourself.

Escape from the ship.

Uncover the secret in the old house.

Escape from the guest house.

Fight off Marguerite while she wanders the old house to make her run away.

Complete the game within 4 hours.

Complete the game on Normal.

Destroy all Mr. Everywhere statuettes.