Die in the 'Into the Abyss' level 3 times in a row

Completed every level in Winter Blunderland

Earned 3 free balls on one shot (Except Trials and Multiplayer)

Get at least rank S on any level on hard difficulty without any modifiers.

Give the patient heterochromia.

Complete a brain transplant by throwing it in.

Go about your secretarial duties.

Obtain the Persona Arsene.

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Finish the Seventh Lifetime

Perform a Leap of Faith from the Top of Florence's Giotto's Campanile.

Enter the Animus 2.0.

Be reborn as Ezio Auditore Da Firenze.