Complete a Speedrun of Chapter 1 below the target time.

Attain a Time Trial star rating of 20

Collected all other BioShock trophies

Complete the game on Hard difficulty without using a Vita-Chamber

The player has completed the game on the Hard difficulty setting

The player has defeated Atlas

Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks

The player has either Harvested or Rescued every possible Little Sister

Acquire all upgrades for all weapons

The player has entered Sander Cohen's personal quarters

Fully upgrade five weapons

Fully upgrade four weapons

The player has fully upgraded three weapons