The player has completed Sander Cohen's great masterpiece

The player has successfully invented all possible ammo types

The player has fully upgraded one weapon

Hit the jackpot at a slot machine

Fully research the Rosie

The player has fully researched the Thuggish Splicer

The player has acquired at least one weapon upgrade

The player has fully researched the Leadhead Splicer

The player has taken at least one Research Photo of a Splicer

The player has purchased one slot in any Plasmid or Tonic track

The player has successfully hacked a safe

The player has successfully hacked a vending machine

The player has performed at least one successful hack