Replay a Memory.

Throw money in a well.

Achieve 100% Synchronization in any Sequence other than Sequence 1.

Find 1 Artifact in 2012.

Find a secure place to hide and re-enter the Animus.

Attempt to access DNA Sequence 9 for the first time.

Complete all Tutorial Lessons

Unlock all 20 pieces of Subject 16's video.

Wear the Auditore cape in each city.

Tint your clothes with those colors: Wetland Ebony and Wetland Ivory.

Use your Eagle Vision to scan a Glyph in the environment.

Spend 5000 florins on Courtesans.