In the Main Campaign, completed Lighthouse.

Headed to the surface on the side of Sinclair's escape pod.

Found or purchased all 11 basic Plasmid types.

Reunited with your original Little Sister.

Saved every Little Sister and spared Grace, Stanley and Gil.

Dealt with every Little Sister.

Fully upgraded one Plasmid to the Level 3 version.

Gathered 600 ADAM with Little Sisters.

Installed the third upgrade to a weapon.

Bought one Plasmid or Tonic Slot at a Gatherer's Garden.

Confronted Lamb's lieutenant in Pauper's Drop.

Killed an enemy with its own projectile.

Researched a Splicer with the Research Camera.