In the Main Campaign, completed Lighthouse.

The player has broken Fontaine's mind control

The player has fully upgraded one weapon

The player has completed Sander Cohen's great masterpiece

The player has purchased one slot in any Plasmid or Tonic track

The player has acquired at least one weapon upgrade

The player has defeated Peach Wilkins

The player has successfully hacked a safe

The player has taken at least one Research Photo of a Splicer

The player has performed at least one successful hack

The player has successfully completed the Welcome To Rapture Level

Destroy all of the planet models in Drek's office.