Rescued the Little Sister in “Worlds of Hurt” using only plasmids, tonics, the wrench, and the research camera, on Medium or higher difficulty

Charged up the Ferris Wheel 9 different times in “A Shocking Turn of Events”

The player has rescued the Little Sister in “A Shocking Turn of Events” in under 4:00

Found all collectable Roses in “The ‘I’ in Team”

Rescued the Little Sister in “The ‘I’ in Team” without destroying any Machine Gun Turrets

Complete the game on Survivor difficulty without using a Vita-chamber

The player has completed the game on the Hard difficulty setting

The player has completed the game without harvesting any Little Sisters

The player has become a Big Daddy

The player has either Harvested or Rescued every possible Little Sister

Purchased every slot in all four Plasmid and Tonic tracks

Max out all possible research