Rule of Six.

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Defeat 3 Agitator Majini in one playthrough of "Desperate Escape."

Complete "Desperate Escape" on any difficulty setting.

Inflict a set amount of damage to Wesker in "Lost in Nightmares."

Build a siege machine.

Destroy 5 buildings or siege machines.

Immobilize 50 enemy squads.

Complete a Nightmare Dungeon in Torment 2 or higher.

Slow down 300 enemy soldiers using Volley Ability.

Use a throwable item for the first time.