Become the Kill Leader

Finish the game on Expert difficulty

Destroy half the D.U.P. security cameras

Stand up for the helpless

Rescue 10 suspects from suspicion pens

Hit three weak points with Neon Beam in 6 seconds

Complete a District Showdown

The player has completed the game without harvesting any Little Sisters

The player has completed the game on the Hard difficulty setting

Unlocked all trophies

The player has become a Big Daddy

The player has either Harvested or Rescued every possible Little Sister

Purchased every slot in all four Plasmid and Tonic tracks