Hacked one of each kind of machine.

Defended yourself against Lamb's Assault in the train station.

Found your way back into the ruins of Rapture.

Successfully invent at least 100 items

The player has become a Big Daddy

Fully upgrade five weapons

Fully upgrade four weapons

The player has defeated Andrew Ryan

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has completed Sander Cohen's great masterpiece

The player has restored the forests of Arcadia

The player has purchased one slot in any Plasmid or Tonic track

The player has acquired at least one weapon upgrade