Destroy the Machine Gun.

Complete DNA Sequence 3.

Discover the Shrine in Il Colosseo.

Discover the Shrine in the Terme di Traiano.

Find a secure place to hide and re-enter the Animus.

Attempt to access DNA Sequence 9 for the first time.

Wreck a Cop

Complete "On a Pale Horse".

Complete "Cure For Most of What Ails You" and "Get Back in that Hole, Partner" Survivor Missions.

Find and kill a sasquatch.

Mix a drink

Create a combo weapon