Use a whirlpool curse to teleport an enemy that is attacking your town.

Sink two enemy ships with a single bomb.

Destroy a neutral or enemy town's defense with a bomb.

Complete Corinth River on any difficulty level

The player has become a Big Daddy

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has broken Fontaine's mind control

The player has entered Sander Cohen's personal quarters

The player has fully researched the Thuggish Splicer

The player has defeated Andrew Ryan

The player has fully upgraded one weapon

The player has completed Sander Cohen's great masterpiece