Found 100 audio diaries.

Found or purchased all 11 basic Plasmid types.

Bought one Plasmid or Tonic Slot at a Gatherer's Garden.

Gained access to Lamb's stronghold.

Got through a Gather with no damage and no one getting to the Little Sister.

Installed the third upgrade to a weapon.

Fully upgraded one Plasmid to the Level 3 version.

Gathered 600 ADAM with Little Sisters.

Defeated the Preacher.

Confronted Lamb's lieutenant in Pauper's Drop.

Spent 2000 dollars at Vending Machines.

Researched a Splicer with the Research Camera.