The player has acquired at least one weapon upgrade

The player has successfully hacked a security camera

The player has purchased one slot in any Plasmid or Tonic track

Defeat 100 enemies in a row without dying in combat

Complete the campaign on Hardened difficulty.

Assign a settler to a pillory

Reach Maximum Happiness in a Large Settlement

Complete "Rockets' Red Glare"

Complete "Powering Up"

Stop an AST with an EMP grenade.

Collect 10 Vault-Tec Bobbleheads

Hack 50 Terminals

Pick 50 Locks