Purchased every slot in all four Plasmid and Tonic tracks

The player has fully researched the Thuggish Splicer

The player has fully researched the Leadhead Splicer

The player has defeated Andrew Ryan

The player has successfully completed 50 hacks

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has successfully invented all possible ammo types

The player has restored the forests of Arcadia

The player has successfully invented at least one item

The player has defeated Peach Wilkins

The player has purchased one slot in any Plasmid or Tonic track

The player has successfully hacked a safe