Confronted Lamb's lieutenant in Pauper's Drop.

Bought one Plasmid or Tonic Slot at a Gatherer's Garden.

Defended yourself against the Big Sister without dying.

Researched a Splicer with the Research Camera.

Got through a Gather with no damage and no one getting to the Little Sister.

Adopted a new Little Sister for the very first time.

Upgraded a weapon at a Power to the People Station.

Used the Hack Tool to hack an object at a distance.

The player has completed the game without harvesting any Little Sisters

Successfully invent at least 100 items

The player has either Harvested or Rescued every possible Little Sister

Fully upgrade four weapons

The player has broken Fontaine's mind control