Completed "Blood Ties"

Took the G.O.A.T.

You unlocked the special ability of Brucie's helicopter ride.

You completed all 10 package delivery jobs.

You completed the mission "Roman's Sorrow".

Sing your first song

The player has defeated Atlas

The player has either Harvested or Rescued every possible Little Sister

Fully upgrade four weapons

The player has successfully invented all possible ammo types

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has fully researched the Spider Splicer