Enter the Animus 2.0.

Be reborn as Ezio Auditore Da Firenze.

You completed the mission "Museum Piece".

You unlocked all the islands.

You completed the mission "Roman's Sorrow".

You completed the mission "Uncle Vlad".

You have completed the first mission.

Work with a Buddy to subvert a mission offered by a faction

Save a Buddy from captivity

Shoot down a Warhawk with any infantry weapon other than a Rocket Launcher.

Finish story mode on Hard, without changing the difficulty setting.

Good guys put a stop to the madness.