In the Main Campaign, killed 75 enemies either with a Vigor or while the enemy is under the effects of a Vigor.

In the Main Campaign, killed 20 "Heavy Hitter" enemies.

In the Main Campaign, looted 200 containers.

In the Main Campaign, killed 20 enemies with the Barnstormer RPG.

Reached Monument Island.

In the Main Campaign, equipped a piece of Gear in all four slots.

Finished the game without using Vita-Chambers.

Headed to the surface on the side of Sinclair's escape pod.

Reunited with your original Little Sister.

Gained access to Lamb's stronghold.

Fully upgraded one Plasmid to the Level 3 version.

Killed an enemy with its own projectile.

Gathered 600 ADAM with Little Sisters.