Max out any upgradable Support ability

Complete the campaign on any difficulty without shooting any civilians

Find 50% of the collectibles in the campaign

Complete level 'The Handler'

Complete level 'The Helghast'

Complete level 'The Doctor'

Complete level 'The Father'

Finish the game on Dante Must Die Mode

Unlock all the entries for every enemy file in the status menu

Max out the Health Bar

Finish the Game on Hard Mode

Collect 50,000 Red Orbs

Clear a mission without taking damage