The player has fully researched the Spider Splicer

Fully research the Houdini Splicer

The player has fully researched the Leadhead Splicer

Take at least one photo in every research group

The player has completed the game without harvesting any Little Sisters

The player has become a Big Daddy

The player has fully upgraded three weapons

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has fully upgraded two weapons

The player has completed Sander Cohen's great masterpiece

The player has restored the forests of Arcadia

The player has fully upgraded one weapon

The player has acquired at least one weapon upgrade