Find 80 Treasures

Kill an Enemy While Playing as an Alternate Character Costume Other Than Drake

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Defeat 20 Enemies While Swimming

Kill 10 Enemies in a Row, Alternating Hand-to-Hand Combat and Gunfire

Kill 75 Enemies in a Row Without Dying

Kill 4 Enemies with 1 Explosion

Defeat 10 Enemies with Thrown-Back Grenades

Throw Back a Grenade and Defeat 2 Enemies at Once

Activate a Tweak

Beat 'Chapter 16 - One Shot at This' in less than 12 minutes

Beat 'Chapter 7 - Stay in the Light' in less than 9 minutes 30 seconds

Finish the Game on Hard Without Changing the Difficulty